
Ketamine vs. Esketamine: What New Research Means for Depression Treatment
A recent study published on PubMed highlights promising findings in the treatment of depression using intranasal ketamine. Researchers found that racemic ketamine is non-inferior to

Mindbloom Faces Wrongful Death Lawsuit Over At-Home Ketamine Overdose
Telehealth ketamine therapy provider Mindbloom is facing a wrongful-death lawsuit after a 27-year-old male patient died from ketamine toxicity in October 2023, allegedly while under

Ketamine Holds Promise for Cognitive Benefits, Study Shows
For over 50 years, ketamine has been known as a safe anesthetic, and at lower doses, an effective treatment for depression. Emerging research suggests it

Intravenous Ketamine Outperforms Intranasal Esketamine in Depression
A retrospective study of 153 patients with severe treatment-resistant depression found that twice-weekly IV ketamine over 4–5 weeks led to faster and greater symptom reduction

Cleveland Clinic study shows ketamine infusions effective for chronic pain patients
A four-year Cleveland Clinic study of 1,034 patients found that low-dose ketamine infusions significantly improved pain, sleep, and daily function for 20%–46% of people with

Ketamine Safe, Effective For Chronic Pain
A Cleveland Clinic study found that low-dose IV ketamine infusions are safe and effective for chronic pain management. Among more than 1,000 patients, 20%–46% saw

Ketamine for Suicidality: Evidence on Rapid Effects, Mechanisms, and Clinical Considerations
Ketamine has emerged as a promising treatment for suicidal ideation (SI) in patients with major depressive disorder (MDD), showing rapid and sustained reductions in suicidality.

Ketamine Reduces Suicidality-Associated ED Use in Treatment-Resistant Depression
A new Journal of Clinical Psychiatry study from the Mayo Clinic found that ketamine and esketamine treatment can significantly reduce emergency department visits related to

Real-World Effectiveness of Maintenance Ketamine Infusions for Treatment-Resistant Depression in Major Depressive Disorder and Bipolar Disorder
This study followed 135 patients with severe depression—110 with treatment-resistant major depressive disorder (TRD) and 25 with treatment-resistant bipolar depression (TRBD)—who had already responded to

A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder
This study looked at whether ketamine could help people struggling with long-term post-traumatic stress disorder (PTSD). Thirty participants received either six ketamine infusions or a

How Ketamine Works: The Clear Science Behind the Therapy
At Charleston Ketamine Center, we often meet patients who have tried everything, yet still struggle with depression, PTSD, anxiety, or chronic pain such as migraines.

Ketamine Did NOT Kill Matthew Perry…He Drowned While Using Ketamine.
We have been inundated with comments and questions regarding the safety of ketamine due to the tragic death of Matthew Perry. In my opinion, the

Could the Embrace of Psychedelics Lead to a Mental-Health Revolution?
AT SEVEN O’ CLOCK on a recent evening, I dim the bedroom lights, call out a reminder to my boyfriend to rouse me in an hour with a gentle tap, and close the door. “Have a great trip,” I hear him say from the living room

I Tried Ketamine Therapy For Anxiety & This Was My Experience
I’ve shared a lot about my quest to quell anxiety over the years, including in my book, The Joy Plan. Thankfully, daily practices such as mindfulness, meditation, exercise, and a healthy diet have helped me tremendously.

Ketamine: a new chapter in antidepressant development
From the beginning of the neuropsychiatric drug era, the development of antidepressants has been mostly based on serendipity. One of the first examples, iproniazid, was an antitubercular drug observed to induce
