Breakthrough treatment for chronic pain, Complex Regional Pain Syndrome, and severe migraines
Charleston Ketamine Center offers advanced ketamine infusion therapy for patients living with debilitating chronic pain. This includes those diagnosed with Complex Regional Pain Syndrome (CRPS), chronic pain, and migraines that have not responded to traditional medications.

Ketamine for CRPS and Chronic Pain
For patients living with chronic pain that hasn’t responded to conventional treatment, ketamine works differently than anything you’ve likely tried. Rather than masking symptoms, ketamine targets the receptors responsible for pain sensitization and the neurological amplification that keeps the nervous system stuck in a cycle of chronic pain.
Ketamine for Migraines
Chronic migraines—defined as 15 or more headache days per month—can severely limit your ability to function. Many patients cycle through multiple medications with limited success. Research has shown that ketamine, particularly IV infusions, may help those who have not found relief with standard treatments.
Ketamine acts as a central nervous system modulator, dampening overactive pain pathways and reducing inflammation associated with migraine onset. It can be especially effective in cases where migraines are accompanied by central sensitization or medication overuse headaches.
Some benefits patients have experienced include:
- Fewer migraine days per month
- Shorter duration and intensity of attacks
- Decreased reliance on oral medications
- Improved mental clarity and energy
Our team will assess your migraine history and design an infusion protocol aimed at breaking the cycle and preventing future episodes.
What to Expect
Infusions for chronic pain or migraine are typically longer in duration, with initial sessions lasting up to four hours. These may be administered over several consecutive days to reset the body’s pain response. We closely monitor your vitals and response during each session to ensure your safety and comfort.
What Patients Experience
Patients often describe:
- A lift in mood and energy
- Reduction in negative thought patterns
- Increased motivation and emotional stability
- Decreased suicidal thoughts
Unlike medications that take weeks to build up in your system, ketamine often brings clarity and calm within the first few infusions.
Cost and Financing
CRPS, chronic pain, and migraine infusions are $850 per four-hour session. Flexible financing is available through Advance Care and CareCredit. If pain is interfering with your ability to enjoy life or perform daily tasks, ketamine may offer a new path forward.
Find Out If Ketamine Therapy Is Right for You
Charleston Ketamine Center is the leading provider of ketamine treatments in South Carolina, known for our experience, compassion, and patient-first approach. Schedule a free consultation today to learn how ketamine therapy can help you feel like yourself again.
