Clinical Research on Ketamine Therapy

Explore the science behind ketamine’s effectiveness for mental health and chronic pain

At Charleston Ketamine Center, our approach is grounded in science. We offer ketamine therapy based on an ever-growing body of peer-reviewed clinical research that supports its safety and effectiveness for treating depression, anxiety, PTSD, and chronic pain conditions such as CRPS and migraines.

Charleston Ketamine Center has tracked its results with patients in categories ranging from Extreme to Borderline Depression.  Each chart shows a definitive decrease (30% or greater) in close to 4 out of 5 patients trying a series of 6 initial infusions. Scoring based on patients filling out Beck’s Depression Inventory on each visit.

Why Clinical Research Matters

Our protocols are designed using the latest findings from leading academic institutions, neuroscience labs, and medical journals. Ketamine’s rapid antidepressant and analgesic properties have been studied extensively, showing both fast-acting and long-lasting benefits for patients who have not responded to traditional treatments.

  • A 2006 NIH study was the first to show that ketamine produced rapid improvement in treatment-resistant depression.
  • Yale University researchers found that ketamine can create new synaptic connections in the brain, reversing damage from chronic stress and depression.
  • The American Journal of Psychiatry has published multiple articles showing ketamine’s ability to reduce suicidal ideation within hours.
  • Clinical research supports its use for generalized anxiety disorder, PTSD, and OCD, with high response rates and favorable safety profiles.
  • Recent pain studies show ketamine’s ability to modulate NMDA receptors and reduce central sensitization, especially in CRPS and chronic migraine sufferers.

Key Research Findings

  • Ketamine for Treatment-Resistant Depression (TRD)
  • Ketamine for Generalized Anxiety and PTSD
  • Ketamine for Suicidal Ideation
  • Ketamine for Chronic Pain, CRPS, and Migraines
  • Long-term efficacy and maintenance protocols

Research Areas We Support

  • Ketamine for Treatment-Resistant Depression (TRD)
  • Ketamine for Generalized Anxiety and PTSD
  • Ketamine for Suicidal Ideation
  • Ketamine for Chronic Pain, CRPS, and Migraines
  • Long-term efficacy and maintenance protocols

Our Clinical Alignment

Our medical team follows protocols in alignment with the latest clinical standards and collaborates with other ketamine centers and providers nationwide. We routinely evaluate new studies to refine our care model and ensure patients receive the most up-to-date and evidence-based treatment possible.

Have questions about how clinical research applies to your condition? Contact us to schedule a free consultation and learn more about the science behind your treatment plan.